My great-grandmother had my grandmother at 46

My own great-grandmother had my grandmother at 46, (no such thing as donor eggs then), my grandmother had 4 children, 6 grandchildren and currently 10 great grandchildren. All started from a 46 year old egg back in 1900, pretty good!

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I'm 44 (45 next month) and just had my first positive preg test.

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Its just a matter of keep trying, it is more difficult to become and remain pregnant over 40 but by no means impossible and people do it all the time - my friend had her second aged 44.

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Somebody who is 45 isn't by nature going to be as fertile as a 20-year-old, but we would definitely discuss it [getting pregnant] with her and do a health assessment. I would be quite happy with it. I've seen women who thought they were menopausal and hadn't realised they were pregnant. And they have had a perfectly normal pregnancy.

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Some women may be better able to get pregnant naturally after the age of 45 thanks to genes involved in aging. There is a theory that merely having a lot of children can increase the chances of future pregnancies.

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